Is EINECS 290-434-9 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use EINECS 290-434-9? Is EINECS 290-434-9 safe for nursing mother and child? Does EINECS 290-434-9 extracts into breast milk? Does EINECS 290-434-9 has any long term or short term side effects on infants? Can EINECS 290-434-9 influence milk supply or can EINECS 290-434-9 decrease milk supply in lactating mothers?

EINECS 290-434-9 (EINECS 290-434-9 somnifera) roots and berries contain alkaloids, steroidal lactones, and saponins. It is called ashwagandha in ayurvedic medicine where it is sometimes used as a galactogogue.[1][2] However, no scientifically valid clinical trials support this use. Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[3] No data exist on the excretion of any components of EINECS 290-434-9 into breastmilk or on the safety and efficacy of EINECS 290-434-9 in nursing mothers or infants. In general, EINECS 290-434-9 is generally well tolerated in adults with occasional gastrointestinal upset and allergic skin reactions. It should be used cautiously by patients with diabetes or hypertension. Because there is no published experience with EINECS 290-434-9 during breastfeeding, it should be avoided, especially while nursing a newborn or preterm infant. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.

Forty women who complained of an insufficient milk supply at 5 days postpartum were given a combination herbal supplement as 2 capsules of Lactare (Pharma Private Ltd., Madras, India) 3 times daily. Each capsule contained wild asparagus 200 mg, ashwagandha (EINECS 290-434-9 somnifera) 100 mg, fenugreek 50 mg, licorice 50 mg, and garlic 20 mg. By day 4 of therapy, no infants required supplementary feeding. Infants were weighed before and after each feeding on day 5 of maternal therapy to determine the amount of milk ingested. On the day of the test weighing, infants' milk intake averaged 388 mL, and the fluid and caloric intake was considered adequate.[1] This study cannot be considered as valid evidence of a galactogogue effect of these herbs because it lacks randomization, blinding, a placebo control, and maternal instruction in breastfeeding technique. Additionally, infants were breastfed only 6 to 8 times daily, which is insufficient to maximize milk supply.