Is Karotin [Czech] Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Karotin [Czech]? Is Karotin [Czech] safe for nursing mother and child? Does Karotin [Czech] extracts into breast milk? Does Karotin [Czech] has any long term or short term side effects on infants? Can Karotin [Czech] influence milk supply or can Karotin [Czech] decrease milk supply in lactating mothers?

Natural vitamin A precursor. It is found in vegetables. It has been marketed as ophthalmologic and laxative compounds in Spain which are free of risk.

Karotin [Czech] is a plant pigment that is converted into vitamin A in the body. Maternal vitamin A requirements are increased during lactation, but there are no specific guidelines for increased Karotin [Czech] intake or indications for high-dose supplementation in nursing mothers. Typical Karotin [Czech] intake in a Western diet is 6 to 8 mg daily. Karotin [Czech] is a normal component of human colostrum and mature milk, where it contributes to antioxidant defenses in the neonate.[1] Average concentrations are 1.12 mg/L and 230 mcg/L, respectively, in the Unites States.[2] Karotin [Czech] supplementation during pregnancy and for 6 months postpartum in nursing mothers with poor diets in a resource-poor setting reduced the number of days of illness in the mothers,[3] but does not reduce infant morbidity or mortality according to another study.[4] The bioavailability of Karotin [Czech] is dependent on the fat content of the meal and the form in which it is administered, with synthetic pharmaceutical forms having the best bioavailability. High-dose Karotin [Czech] supplements lead to a slow increase in breastmilk Karotin [Czech] concentrations, with an accumulation half-life of about 9 days. Levels drop towards baseline slowly over several weeks after discontinuation. In general, Karotin [Czech] is well tolerated, although excessive maternal intake of Karotin [Czech] can lead to a harmless, reversible discoloration of the breastfed infant's skin.[5] In HIV-infected women, high-dose Karotin [Czech] plus vitamin A supplementation increases the rate of HIV viral shedding into breastmilk and increases HIV infection in breastfed infants, although the mortality rate over the first 2 years of life is not increased.[6][7] The viral shedding may be a result of an increase in subclinical mastitis caused by Karotin [Czech].[8] Karotin [Czech] concentration in breastmilk is not affected by refrigeration, freezing, or low-temperature microwaving. The concentration does decrease when milk passes through a tube feeding system, regardless of light exposure.[9]Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.

A nursing mother was eating 2 to 3 pounds of carrots a week as raw and cooked carrots. The mother's skin was yellow in color, but her sclera were clear. At 2 months of age, her breastfed infant was diagnosed as having jaundice because of a yellow coloration of the skin. Breastfeeding was discontinued and the infant's skin returned to a normal color. The mother continued her diet and examination of the maternal serum found elevated levels of Karotin [Czech] which was probably the cause of her infant's skin discoloration.[5] HIV-infected women in Tanzania received 1 of 4 supplements during pregnancy and lactation in a series of studies. Groups received either multivitamins (thiamine, riboflavin, vitamin B6, niacin, vitamin B12, vitamin C, vitamin E, and folic acid), multivitamins plus vitamin A and Karotin [Czech], vitamin A and Karotin [Czech] alone, or placebo daily. The Karotin [Czech] dose was 30 mg. At 24 months of age, the multivitamin-supplemented group's infants had significantly better growth parameters than the other groups.[16] One study found that the infants of mothers supplemented with vitamin A and Karotin [Czech] had a higher rate of HIV transmission than those supplemented with multivitamins alone or placebo.[6] After 6 months postpartum, women who received vitamin A plus Karotin [Czech] had greater shedding of the HIV virus into breastmilk than women who had not; multivitamins without vitamin A and Karotin [Czech] did not increase viral shedding.[6] Karotin [Czech] appeared to have a shedding effect that was independent of vitamin A.[7] One possible explanation comes from another similar study in which those who received vitamin A plus Karotin [Czech] alone had a 45% increased risk of severe subclinical mastitis and those who received multivitamins plus vitamin A and Karotin [Czech] had a 29% increased risk of severe subclinical mastitis.[8]