Is Sibutramina Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Sibutramina? Is Sibutramina safe for nursing mother and child? Does Sibutramina extracts into breast milk? Does Sibutramina has any long term or short term side effects on infants? Can Sibutramina influence milk supply or can Sibutramina decrease milk supply in lactating mothers?

• DrLact safety Score for Sibutramina is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of Sibutramina may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that Sibutramina may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using Sibutramina .
• It is recommended to evaluate the advantage of not breastfeeding while using Sibutramina Vs not using Sibutramina And continue breastfeeding.
• While using Sibutramina Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

On latest update relevant published data on breastfeeding were not found. Because of high protein-binding, excretion into breast milk seems unlikely. Medication used as anorexigen. Amphetamine-like drug that acts as reuptake inhibitor of Serotonin, Norepinephrine and Dopamine. May cause increase of Prolactin and Galactorrhea. Because of cardiovascular side effects (Arrhythmia, Hypertension, Heart infarction) several regulatory agencies (EMEA, FDA) have withdrawn it from the market in many countries. Breastfeeding mothers return to their pre- pregnancy body weight sooner than others who don't.

Because there is no published experience with Sibutramina during breastfeeding, an alternate therapy may be preferred, especially while nursing a newborn or preterm infant. Information on the effect of Sibutramina on serum prolactin is somewhat conflicting.

In a study of hypocaloric diet plus Sibutramina in overweight and obese patients with polycystic ovary syndrome, no change was seen in serum prolactin levels over the 6-month study period.[1] A woman developed amenorrhea-galactorrhea syndrome shortly after starting therapy with Sibutramina for weight loss. Her serum prolactin was elevated, but returned to normal within 15 days of discontinuing Sibutramina. It remained in the normal range during the 180-day follow-up period.[2] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.