Is N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester)? Is N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) safe for nursing mother and child? Does N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) extracts into breast milk? Does N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) has any long term or short term side effects on infants? Can N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) influence milk supply or can N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) decrease milk supply in lactating mothers?
N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) lactation summary
- DrLact safety Score for N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) usage in lactation
Anti-protozoan drug which is used for treatment of Cryptosporidiosis, Giardia lamblia infection, Intestinal Amoeba Disease, Blastocystis, Leishmaniasis of skin and Microsporidiosis. Excreted into breast milk in non-significant clinical amount. The use is authorized for children older than 1 year. Likely side-effects are mild and infrequent (abdominal pain, diarrhea, vomiting)
Answer by DrLact: About N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) usage in lactation
Limited information indicates that a maternal dose of 500 mg of N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester) produces low levels of an active metabolite, tizoxanide, in breastmilk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. But until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Alternate Drugs
Cephradine(Safe)
Azithromycin(Safe)
Didanosine(Unsafe)
Methicillin(Low Risk)
Cefdinir(Safe)
Tetracycline(Safe)
Teicoplanin(Safe)
Sulconazole(Safe)
Cephalexin(Safe)
Acyclovir(Safe)
Meropenem(Safe)
Mebendazole(Safe)
Cefazolin(Safe)
Saquinavir(Unsafe)
Streptomycin(Safe)
Fusidic Acid(Safe)
Polymyxin B(Safe)
Cefuroxime(Safe)
Primaquine(Low Risk)
Loracarbef(Safe)
Colistimethate(Safe)
Cefadroxil(Safe)
Paromomycin(Safe)
Oxiconazole(Safe)
Quinine(Safe)
Lomefloxacin(Low Risk)
Tinidazole(Safe)
Cefaclor(Safe)
Ritonavir(Unsafe)
Procaine Penicillin G(Safe)
Naftifine(Safe)
Ceftriaxone(Safe)
Abacavir(Safe)
Levofloxacin(Low Risk)
Nitazoxanide(Safe)
Sulfasalazine(Safe)
Piperacillin(Safe)
Ciclopirox(Safe)
Atovaquone(Low Risk)
Pyrimethamine(Safe)
Oseltamivir(Safe)
Kanamycin(Safe)
Rifaximin(Safe)
Metronidazole(Safe)
Nevirapine(Low Risk)
Butoconazole(Safe)
Ceftibuten(Safe)
Linezolid(Low Risk)
Chloramphenicol(Unsafe)
Amantadine(Low Risk)
Bacampicillin(Safe)
Nelfinavir(Unsafe)
Penicillin V(Safe)
Ceftazidime(Safe)
Mefloquine(Safe)
Roxithromycin(Safe)
Aztreonam(Safe)
Penicillin G(Safe)
Albendazole(Safe)
Cefprozil(Safe)
Gentamicin(Safe)
Sulfamethoxazole(Safe)
Ampicillin(Safe)
Oxytetracycline(Safe)
Telithromycin(Unsafe)
Gatifloxacin(Low Risk)
Sulfisoxazole(Safe)
Lamivudine(Safe)
Ivermectin(Safe)
Cefoxitin(Safe)
Dapsone(Low Risk)
Hydroxychloroquine(Safe)
Enoxacin(Low Risk)
Vancomycin(Safe)
Amoxicillin(Safe)
Indinavir(Unsafe)
Ofloxacin(Safe)
Cefotetan(Safe)
Capreomycin(Low Risk)
Econazole(Safe)
Doxycycline(Low Risk)
Penciclovir(Safe)
Norfloxacin(Safe)
Salicylic Acid(Safe)
Lindane(Unsafe)
Cefotaxime(Safe)
Ertapenem(Safe)
Chloroquine(Safe)
Valganciclovir(Low Risk)
Dicloxacillin(Safe)
Famciclovir(Low Risk)
Amikacin(Safe)
Neomycin(Safe)
Zidovudine(Low Risk)
Trovafloxacin(Unsafe)
Ganciclovir(Low Risk)
Demeclocycline(Low Risk)
Erythromycin(Low Risk)
Nafcillin(Safe)
Malathion(Low Risk)
Permethrin(Safe)
Cefixime(Safe)
Tobramycin(Safe)
Tioconazole(Safe)
Cloxacillin(Safe)
Clindamycin(Low Risk)
Floxacillin(Safe)
Emtricitabine(Safe)
Moxifloxacin(Low Risk)
Cefepime(Safe)
Tenofovir(Safe)
Ticarcillin(Safe)
Ciprofloxacin(Safe)
Clarithromycin(Safe)
Efavirenz(Unsafe)
Praziquantel(Safe)
Secnidazole(Safe)
Terconazole(Safe)
Mebendazole(Safe)
Primaquine(Low Risk)
Quinine(Safe)
Atovaquone(Low Risk)
Nitazoxanide(Safe)
Pyrimethamine(Safe)
Mefloquine(Safe)
Albendazole(Safe)
Ivermectin(Safe)
Hydroxychloroquine(Safe)
Pyrantel(Safe)
Lindane(Unsafe)
Chloroquine(Safe)
Malathion(Low Risk)
Permethrin(Safe)
Benznidazole(Safe)
Praziquantel(Safe)