Is Ziprasidone Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Ziprasidone? Is Ziprasidone safe for nursing mother and child? Does Ziprasidone extracts into breast milk? Does Ziprasidone has any long term or short term side effects on infants? Can Ziprasidone influence milk supply or can Ziprasidone decrease milk supply in lactating mothers?

• DrLact safety Score for Ziprasidone is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of Ziprasidone may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that Ziprasidone may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using Ziprasidone .
• It is recommended to evaluate the advantage of not breastfeeding while using Ziprasidone Vs not using Ziprasidone And continue breastfeeding.
• While using Ziprasidone Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

No data on transfer into breastmilk are available. Indicated for treatment of schizophrenia. It may lengthen QT interval.

Because there is little published experience with ziprasidone during breastfeeding, other antipsychotic agents are preferred, especially while nursing a newborn or preterm infant.[1]

A woman took ziprasidone 40 mg and citalopram 60 mg daily throughout pregnancy and postpartum. She breastfed extensively, except for occasional formula feedings by others. At 6 months of age, a pediatrician found the infant to be healthy with normal growth and development.[3]

Prolactin elevation has occurred during ziprasidone treatment,[4][5][6][7][8][9] and galactorrhea has been reported, often in adolescents.[4][5][6][7][10][11] However, prolactin elevation might be more transient and less severe than with phenothiazines.[12][13][14] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.