Question

I am a breastfeeding mother and i want to know if it is safe to use Itralek? Is Itralek safe for nursing mother and child? Does Itralek extracts into breast milk? Does Itralek has any long term or short term side effects on infants? Can Itralek influence milk supply or can Itralek decrease milk supply in lactating mothers?

Itralek lactation summary

Itralek is safe in breastfeeding
  • DrLact safety Score for Itralek is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Itralek is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Itralek does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Itralek safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Itralek usage in lactation

Pharmacokinetic data (moderately high molecular weight and high protein binding capacity) explain its nil or negligible amount observed in breast milk (McNamara, 2004), such that a breastfed infant would receive a maximum of 35 micrograms per day of Itralek, amount which is a hundred times lower than the pediatric dose of 5 mg / kg / day currently recommended (Janssen Cazzaniga 2014 and 1996) Both, low oral bioavailability and alkaline pH hinder its absorption from ingested milk. It is used to treat fungal infections in children, including premature babies, with a good tolerance. Itralek significantly increases plasma concentrations of Domperidone, which must be taken into account in case of simultaneous administration of both drugs.

Answer by DrLact: About Itralek usage in lactation

No information is available on the clinical use of Itralek during breastfeeding. However, limited data indicate that maternal Itralek produces levels in milk that are less than the 5 mg/kg daily doses that have been recommended to treat infants. Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.