Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-37CQ2C7X93? Is UNII-37CQ2C7X93 safe for nursing mother and child? Does UNII-37CQ2C7X93 extracts into breast milk? Does UNII-37CQ2C7X93 has any long term or short term side effects on infants? Can UNII-37CQ2C7X93 influence milk supply or can UNII-37CQ2C7X93 decrease milk supply in lactating mothers?

Answer by DrLact: About UNII-37CQ2C7X93 usage in lactation

No information is available on the passage of UNII-37CQ2C7X93 into breastmilk. Because UNII-37CQ2C7X93 is a large protein molecule with a molecular weight of 145,157, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, UNII-37CQ2C7X93 injection should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Topical or homeopathic preparations pose little risk to the nursing infant. UNII-37CQ2C7X93 is a human immunoglobulin G1 (IgG1) kappa antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%.[1][2] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Specific IgG subclasses decreased by different amounts, with IgG1 activity decreasing by about 37%.[3] None of the studies measured IgG activity.

UNII-37CQ2C7X93 Side Effects in Breastfeeding

In an international multicenter study of mothers exposed to interleukin-1 receptor antagonists, 4 babies were breastfed (extent not stated) by mothers receiving regular UNII-37CQ2C7X93. It is unclear if mothers received the drug postpartum or only during pregnancy. There were no reported serious infections and no developmental abnormalities at a mean follow-up of 2.2 years (range 5 months to 4 years).[4]
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