I am a breastfeeding mother and i want to know if it is safe to use Arzerra Injection? Is Arzerra Injection safe for nursing mother and child? Does Arzerra Injection extracts into breast milk? Does Arzerra Injection has any long term or short term side effects on infants? Can Arzerra Injection influence milk supply or can Arzerra Injection decrease milk supply in lactating mothers?
No information is available on the clinical use of Arzerra Injection during breastfeeding. Because Arzerra Injection is a large protein molecule with a molecular weight of 149,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, Arzerra Injection should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Arzerra Injection is a human immunoglobulin G1 (IgG1) kappa antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%.[1][2] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Specific IgG subclasses decreased by different amounts, with IgG1 activity decreasing by about 37%.[3] None of the studies measured IgG activity.
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