Is Perjeta Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Perjeta? Is Perjeta safe for nursing mother and child? Does Perjeta extracts into breast milk? Does Perjeta has any long term or short term side effects on infants? Can Perjeta influence milk supply or can Perjeta decrease milk supply in lactating mothers?
Answer by DrLact: About Perjeta usage in lactation
No information is available on the clinical use of Perjeta during breastfeeding. Because Perjeta is a large protein molecule with a molecular weight of about 148,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, Perjeta should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during Perjeta therapy and for 7 months after the last dose.
Alternate Drugs
Omalizumab(Low Risk)
Rituximab(Low Risk)
Ustekinumab(Low Risk)
Bevacizumab(Low Risk)
Natalizumab(Low Risk)
Trastuzumab(Unsafe)
Certolizumab Pegol(Safe)
Denosumab(Low Risk)
Infliximab(Safe)
Ipilimumab(Unsafe)
Abciximab(Low Risk)
Basiliximab(Low Risk)
Belimumab(Low Risk)
Secukinumab(Low Risk)
Brentuximab Vedotin(Low Risk)
Nivolumab(Unsafe)
Cetuximab(Unsafe)
Ranibizumab(Safe)