Is Fabrazyme Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Fabrazyme? Is Fabrazyme safe for nursing mother and child? Does Fabrazyme extracts into breast milk? Does Fabrazyme has any long term or short term side effects on infants? Can Fabrazyme influence milk supply or can Fabrazyme decrease milk supply in lactating mothers?

No information is available on the clinical use of Fabrazyme during breastfeeding. Because it is a large protein molecule with a molecular weight of about 100,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Six infants who were breastfed for periods up to 12 months by mothers taking the closely related drug agalsidase alfa experienced no adverse effects associated with the drug.

Published information on Fabrazyme was not found as of the revision date. However, some information is available on the closely related drug agalsidase alfa. Six patients with Fabray disease were treated with agalsidase alfa 0.2 mg/kg every 2 weeks during pregnancy and postpartum. One infant partially breastfed for 10 months had asthma at age 4 years and an infant who was partially breastfed for 5 months had recurrent urinary tract infections up to 2 years, but was normal at the age of 5 years. Threee infants who were exclusively breastfed for 6 months and partially breastfed until 12 months and one partially breastfed for 12 months were normal. None of the adverse effects appear to have been associated with agalsidase alfa.[1]