Is Bisoprolol Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Bisoprolol? Is Bisoprolol safe for nursing mother and child? Does Bisoprolol extracts into breast milk? Does Bisoprolol has any long term or short term side effects on infants? Can Bisoprolol influence milk supply or can Bisoprolol decrease milk supply in lactating mothers?
Bisoprolol lactation summary
- DrLact safety Score for Bisoprolol is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Bisoprolol may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Bisoprolol may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Bisoprolol low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Bisoprolol We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Bisoprolol usage in lactation
One case with no traces of this drug in the mother's milk has been reported. Until more information is available, safer options should be preferred.
Answer by DrLact: About Bisoprolol usage in lactation
Because there is little published experience with bisoprolol during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Bisoprolol Side Effects in Breastfeeding
A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking bisoprolol.[3] Beta-adrenergic blocking drugs with similar breastmilk excretion characteristics have caused adverse effects in breastfed newborns.[4][5]
Bisoprolol Possible Effects in Breastfeeding
A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[6] Relevant published information on the effects of beta-blockade or bisoprolol during normal lactation was not found as of the revision date.
Alternate Drugs
Bisoprolol(Low Risk)
Metoprolol(Safe)
Sotalol(Low Risk)
Atenolol(Unsafe)
Propranolol(Safe)
Levobunolol(Low Risk)
Acebutolol(Unsafe)
Labetalol(Safe)
Carteolol(Unsafe)
Nebivolol(Unsafe)
Carvedilol(Low Risk)
Nadolol(Unsafe)
Timolol(Safe)
Diltiazem(Safe)
Sotalol(Low Risk)
Digoxin(Safe)
Quinidine(Safe)
Propranolol(Safe)
Atenolol(Unsafe)
Levobunolol(Low Risk)
Propafenone(Low Risk)
Procainamide(Safe)
Acebutolol(Unsafe)
Labetalol(Safe)
Verapamil(Safe)
Flecainide(Safe)
Nadolol(Unsafe)
Lidocaine(Safe)
Amiodarone(Unsafe)
Timolol(Safe)
Disopyramide(Safe)
Bisoprolol(Low Risk)
Mexiletine(Safe)
Metoprolol(Safe)
Timolol(Safe)
Telmisartan(Unsafe)
Spironolactone(Safe)
Diltiazem(Safe)
Bisoprolol(Low Risk)
Prazosin(Unsafe)
Methyldopa(Safe)
Metoprolol(Safe)
Reserpine(Unsafe)
Ramipril(Low Risk)
Sotalol(Low Risk)
Losartan(Low Risk)
Lisinopril(Low Risk)
Chlorthalidone(Dangerous)
Irbesartan(Unsafe)
Isradipine(Low Risk)
Chlorothiazide(Safe)
Indapamide(Low Risk)
Captopril(Safe)
Atenolol(Unsafe)
Eprosartan(Low Risk)
Propranolol(Safe)
Bumetanide(Low Risk)
Doxazosin(Safe)
Hydrochlorothiazide(Safe)
Levobunolol(Low Risk)
Hydralazine(Safe)
Acebutolol(Unsafe)
Guanfacine(Low Risk)
Furosemide(Low Risk)
Bosentan(Low Risk)
Nitrendipine(Safe)
Fosinopril(Low Risk)
Labetalol(Safe)
Nisoldipine(Low Risk)
Bendroflumethiazide(Unsafe)
Verapamil(Safe)
Nebivolol(Unsafe)
Nimodipine(Safe)
Benazepril(Safe)
Nicardipine(Safe)
Felodipine(Low Risk)
Nifedipine(Safe)
Amlodipine(Low Risk)
Trandolapril(Dangerous)
Enalapril(Safe)
Carvedilol(Low Risk)
Valsartan(Low Risk)
Minoxidil(Safe)
Nadolol(Unsafe)
Torsemide(Low Risk)
Terazosin(Unsafe)