Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 5102? Is HSDB 5102 safe for nursing mother and child? Does HSDB 5102 extracts into breast milk? Does HSDB 5102 has any long term or short term side effects on infants? Can HSDB 5102 influence milk supply or can HSDB 5102 decrease milk supply in lactating mothers?

HSDB 5102 lactation summary

HSDB 5102 is safe in breastfeeding
  • DrLact safety Score for HSDB 5102 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of HSDB 5102 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that HSDB 5102 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of HSDB 5102 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 5102 usage in lactation

Hydroxide complex formed by HSDB 5102 for parenteral administration.In addition to its high molecular weight, other characteristics of iron metabolism in the body make unlikely that it would be excreted in a significant amount into breast milk.It is a medication used for treatment of Neonatal Anemia in premature babies. Iron is excreted in small amounts in human milk, usually being enough for covering the daily needs of infants due to its high bioavailability. There is no correlation between mother's daily intake of iron and its concentration in breast milk.Iron supplementation to the mother does not increase levels of iron in breast milk or infant plasma significantly. Excessive supplementation can reduce the zinc concentration in milk. WHO List of Essential Medicines 2002: compatible with breastfeeding.

Answer by DrLact: About HSDB 5102 usage in lactation

Limited data indicate that trace amounts of HSDB 5102 are excreted into breastmilk. No information is available on the clinical use of HSDB 5102 during breastfeeding. However, intravenous HSDB 5102 has been used in preterm infants for anemia of prematurity and would not be expected to cause any adverse effects in breastfed infants. An alternate intravenous drug with more published data available may be preferred. Pasteurization of milk by the Holder method reduces the concentration of iron in milk by about 6.5%.[1]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.