Is LU-200134 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use LU-200134? Is LU-200134 safe for nursing mother and child? Does LU-200134 extracts into breast milk? Does LU-200134 has any long term or short term side effects on infants? Can LU-200134 influence milk supply or can LU-200134 decrease milk supply in lactating mothers?
LU-200134 lactation summary
- DrLact safety Score for LU-200134 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of LU-200134 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that LU-200134 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of LU-200134 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About LU-200134 usage in lactation
IgG1-monoclonal antibody directed against tumor necrosis factor used for treatment of auto-immune diseases like Rheumatoid Arthritis. Minimal or low excretion into breast milk due to high molecular weight. In breastfed babies whose mothers were on this medication plasma levels were undetectable and failed to show side effects. It should be avoid in the first two post-partum weeks since pass of significant amounts of IgG to the milk can occur in the first 3 - 4 post-partum days.