Is HSDB 8255 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use HSDB 8255? Is HSDB 8255 safe for nursing mother and child? Does HSDB 8255 extracts into breast milk? Does HSDB 8255 has any long term or short term side effects on infants? Can HSDB 8255 influence milk supply or can HSDB 8255 decrease milk supply in lactating mothers?

• DrLact safety Score for HSDB 8255 is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of HSDB 8255 may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that HSDB 8255 may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using HSDB 8255 .
• It is recommended to evaluate the advantage of not breastfeeding while using HSDB 8255 Vs not using HSDB 8255 And continue breastfeeding.
• While using HSDB 8255 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

On latest update relevant data on breastfeeding was not found. Pharmacokinetic data (high molecular weight but low protein binding) indicates that drug excretion into breast milk would be moderately high. Low oral biodisponibility would be protective for breastfed children who are not newborn or premature. Until new data is available nursing should be delayed for a 5-half lives period (150 hours - 6 to 7 days) after last intake.

In one patient, HSDB 8255 was not detected in the colostrum of a mother taking HSDB 8255; however, no information is available on the use of HSDB 8255 during breastfeeding. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.