Is UNII-S5VXA428R4 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-S5VXA428R4? Is UNII-S5VXA428R4 safe for nursing mother and child? Does UNII-S5VXA428R4 extracts into breast milk? Does UNII-S5VXA428R4 has any long term or short term side effects on infants? Can UNII-S5VXA428R4 influence milk supply or can UNII-S5VXA428R4 decrease milk supply in lactating mothers?
UNII-S5VXA428R4 lactation summary
- DrLact safety Score for UNII-S5VXA428R4 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-S5VXA428R4 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-S5VXA428R4 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-S5VXA428R4 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-S5VXA428R4 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-S5VXA428R4 usage in lactation
UNII-S5VXA428R4 or S-licarbazepine is the S-enantiomer of licarbazepine (MHD), the active metabolite of oxcarbazepine (see specific information), an anti-epileptic drug considered to be of low risk during breastfeeding. Since the last update we have not found any published data on its excretion in breast milk. Given the structural equivalence and similar actions to oxcarbazepine, different effects are not likely in infants who are breastfed by mothers undergoing treatment with UNII-S5VXA428R4 or oxcarbazepine, but until there is more data on this drug in relation to breastfeeding, safer known alternatives are preferred, especially in the neonatal period and in case of prematurity.
Answer by DrLact: About UNII-S5VXA428R4 usage in lactation
No information is available on the use of UNII-S5VXA428R4 during breastfeeding. However, UNII-S5VXA428R4 is the active metabolite of oxcarbazepine. Limited information indicates that oxcarbazepine would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. Monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of anticonvulsants.
UNII-S5VXA428R4 Side Effects in Breastfeeding
No specific information is available in mothers taking UNII-S5VXA428R4. See the LactMed record on oxcarbazepine for relevant information.
Alternate Drugs
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Zonisamide(Low Risk)
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Riluzole(Unsafe)
Topiramate(Safe)
Primidone(Low Risk)
Phenytoin(Safe)
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Phenobarbital(Low Risk)
Oxcarbazepine(Safe)
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Lamotrigine(Low Risk)
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