Is huMAB(CD20) Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use huMAB(CD20)? Is huMAB(CD20) safe for nursing mother and child? Does huMAB(CD20) extracts into breast milk? Does huMAB(CD20) has any long term or short term side effects on infants? Can huMAB(CD20) influence milk supply or can huMAB(CD20) decrease milk supply in lactating mothers?
Answer by DrLact: About huMAB(CD20) usage in lactation
No information is available on the clinical use of huMAB(CD20) during breastfeeding. Because huMAB(CD20) is a large protein molecule with a molecular weight of about 150,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, huMAB(CD20) should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.[1] The manufacturer recommends that breastfeeding be discontinued during huMAB(CD20) therapy.
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