Question

I am a breastfeeding mother and i want to know if it is safe to use BRN 0759821? Is BRN 0759821 safe for nursing mother and child? Does BRN 0759821 extracts into breast milk? Does BRN 0759821 has any long term or short term side effects on infants? Can BRN 0759821 influence milk supply or can BRN 0759821 decrease milk supply in lactating mothers?

BRN 0759821 lactation summary

BRN 0759821 is safe in breastfeeding
  • DrLact safety Score for BRN 0759821 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of BRN 0759821 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that BRN 0759821 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of BRN 0759821 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About BRN 0759821 usage in lactation

Benzodiazepine of short-term action. It is excreted into breastmilk in clinically non-significant amount without problems been observed in infants from treated mothers (Humpel 1982, Lemmer 2007). Drug plasma levels in these infants were undetectable or either very low (Humpel 1982). Infrequent use and a low dose of benzodiazepines is compatible with breastfeeding. Short-acting Benzodiazepines should be chosen along with a minimum effective dose as possible, especially in the neonatal period. Assess for drowsiness and inappropriate infant feeding pattern. It is not recommended bed-sharing with your baby if you are on this medication.

Answer by DrLact: About BRN 0759821 usage in lactation

BRN 0759821 is not approved for marketing in the United States by the U.S. Food and Drug Administration. BRN 0759821 has low levels in breastmilk and a short half-life relative to many other benzodiazepines. Limited evidence from nursing mothers indicates that lorazepam does not cause any adverse effects in breastfed infants with usual maternal dosages. No special precautions are required.

BRN 0759821 Side Effects in Breastfeeding

Five women who were 2 to 3 days postpartum took 2 mg of BRN 0759821 daily at 8 pm for 10 days and fully breastfed their infants. The authors of the study noted no pharmacological or adverse effects in any of the infants during the study.[1]

Alternate Drugs

Oxazepam(Safe)
Alprazolam(Low Risk)
Midazolam(Safe)
Lorazepam(Safe)
Temazepam(Low Risk)
Meprobamate(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Clonazepam(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Midazolam(Safe)
Clobazam(Low Risk)
Lorazepam(Safe)
Estazolam(Low Risk)
Flurazepam(Unsafe)
Temazepam(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Secobarbital(Low Risk)
Oxazepam(Safe)
Propofol(Safe)
Alprazolam(Low Risk)
Ketamine(Low Risk)
Midazolam(Safe)
Chloral Hydrate(Low Risk)
Estazolam(Low Risk)
Zolpidem(Safe)
Zaleplon(Safe)
Flurazepam(Unsafe)
Lorazepam(Safe)
Triazolam(Low Risk)
Eszopiclone(Low Risk)
Sodium Oxybate(Low Risk)
Meprobamate(Low Risk)
Temazepam(Low Risk)
Butalbital(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Butabarbital(Low Risk)
Clorazepate(Low Risk)
Phenobarbital(Low Risk)
Pentobarbital(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.