Question

I am a breastfeeding mother and i want to know if it is safe to use 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one? Is 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one safe for nursing mother and child? Does 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one extracts into breast milk? Does 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one has any long term or short term side effects on infants? Can 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one influence milk supply or can 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one decrease milk supply in lactating mothers?

1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one lactation summary

1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one is unsafe in breastfeeding
  • DrLact safety Score for 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one .
  • It is recommended to evaluate the advantage of not breastfeeding while using 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one Vs not using 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one And continue breastfeeding.
  • While using 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one usage in lactation

Eventual and low dose use of benzodiacepines are compatible with breastfeeding. Use the short-acting benzodiazepine and minimal effective dose as possible mostly in the neonatal period. Follow-up for sedation and feeding ability of the infant. Bed-sharing is not recommended for mothers who are taking this medication.

Answer by DrLact: About 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one usage in lactation

1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one is not approved for marketing in the United States by the U.S. Food and Drug Administration. It is excreted into breastmilk and, because of its long half-life of about 20 hours, it may accumulate in the serum of breastfed infants with repeated doses. Other agents are preferred, especially while nursing a newborn or preterm infant. After a single dose of 1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one, as for sedation before a procedure, there is usually no need to wait to resume breastfeeding, although with a newborn or preterm infant, a cautious approach would be to wait a period of 6 to 8 hours before resuming nursing.

Alternate Drugs

Temazepam(Low Risk)
Meprobamate(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Midazolam(Safe)
Lorazepam(Safe)
Flurazepam(Unsafe)
Temazepam(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Clonazepam(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Midazolam(Safe)
Clobazam(Low Risk)
Lorazepam(Safe)
Estazolam(Low Risk)
Flurazepam(Unsafe)
Lorazepam(Safe)
Triazolam(Low Risk)
Eszopiclone(Low Risk)
Sodium Oxybate(Low Risk)
Meprobamate(Low Risk)
Temazepam(Low Risk)
Butalbital(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Butabarbital(Low Risk)
Quazepam(Unsafe)
Pentobarbital(Low Risk)
Clorazepate(Low Risk)
Phenobarbital(Low Risk)
Secobarbital(Low Risk)
Propofol(Safe)
Oxazepam(Safe)
Alprazolam(Low Risk)
Ketamine(Low Risk)
Chloral Hydrate(Low Risk)
Midazolam(Safe)
Zolpidem(Safe)
Estazolam(Low Risk)
Zaleplon(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.