Question

I am a breastfeeding mother and i want to know if it is safe to use Ro 5-3059? Is Ro 5-3059 safe for nursing mother and child? Does Ro 5-3059 extracts into breast milk? Does Ro 5-3059 has any long term or short term side effects on infants? Can Ro 5-3059 influence milk supply or can Ro 5-3059 decrease milk supply in lactating mothers?

Ro 5-3059 lactation summary

Ro 5-3059 usage has low risk in breastfeeding
  • DrLact safety Score for Ro 5-3059 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Ro 5-3059 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Ro 5-3059 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Ro 5-3059 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Ro 5-3059 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Ro 5-3059 usage in lactation

Eventual and low dose use of benzodiacepines are compatible with breastfeeding. Use the short-acting benzodiazepine and minimal effective dose as possible mostly in the neonatal period. Follow-up for sedation and feeding ability of the infant. Bed-sharing is not recommended for mothers who are taking this medication.

Answer by DrLact: About Ro 5-3059 usage in lactation

Ro 5-3059 is not approved for marketing in the United States by the U.S. Food and Drug Administration. It is excreted into breastmilk in small amounts. Because of its long half-life of about 30 hours, it may accumulate in the serum of breastfed infants with repeated doses. Other agents are preferred, especially while nursing a newborn or preterm infant.

Alternate Drugs

Midazolam(Safe)
Lorazepam(Safe)
Temazepam(Low Risk)
Meprobamate(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Midazolam(Safe)
Clobazam(Low Risk)
Lorazepam(Safe)
Estazolam(Low Risk)
Temazepam(Low Risk)
Flurazepam(Unsafe)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Clonazepam(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Alprazolam(Low Risk)
Ketamine(Low Risk)
Chloral Hydrate(Low Risk)
Midazolam(Safe)
Zolpidem(Safe)
Estazolam(Low Risk)
Zaleplon(Safe)
Triazolam(Low Risk)
Flurazepam(Unsafe)
Lorazepam(Safe)
Eszopiclone(Low Risk)
Sodium Oxybate(Low Risk)
Meprobamate(Low Risk)
Temazepam(Low Risk)
Butalbital(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Butabarbital(Low Risk)
Phenobarbital(Low Risk)
Pentobarbital(Low Risk)
Clorazepate(Low Risk)
Secobarbital(Low Risk)
Propofol(Safe)
Oxazepam(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.