Is 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on? Is 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on safe for nursing mother and child? Does 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on extracts into breast milk? Does 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on has any long term or short term side effects on infants? Can 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on influence milk supply or can 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on decrease milk supply in lactating mothers?
2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on lactation summary
- DrLact safety Score for 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on usage in lactation
Eventual and low dose use of benzodiacepines are compatible with breastfeeding. Use the short-acting benzodiazepine and minimal effective dose as possible mostly in the neonatal period. Follow-up for sedation and feeding ability of the infant. Bed-sharing is not recommended for mothers who are taking this medication.
Answer by DrLact: About 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on usage in lactation
2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-on is not approved for marketing in the United States by the U.S. Food and Drug Administration. It is excreted into breastmilk in small amounts. Because of its long half-life of about 30 hours, it may accumulate in the serum of breastfed infants with repeated doses. Other agents are preferred, especially while nursing a newborn or preterm infant.
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