Question

I am a breastfeeding mother and i want to know if it is safe to use O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate? Is O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate safe for nursing mother and child? Does O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate extracts into breast milk? Does O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate has any long term or short term side effects on infants? Can O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate influence milk supply or can O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate decrease milk supply in lactating mothers?

O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate lactation summary

O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate usage has low risk in breastfeeding
  • DrLact safety Score for O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate usage in lactation

Significantly less O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate penetrated from Ovide after 0.5 h versus the suggested 8 h application, without decreasing the product’s efficacy. Avoid applying it on the breast or nipple. Otherwise, cleanse it thoroughly before nursing.

Answer by DrLact: About O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate usage in lactation

O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate appears to be poorly absorbed after topical application, so it is not likely to reach the breastmilk in large amounts. However, breastmilk excretion of O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate has not been studied after application of the 0.5% lotion. Until more data become available, an alternate agent is preferred.[1]

Alternate Drugs

Aztreonam(Safe)
Indinavir(Unsafe)
Cefprozil(Safe)
Capreomycin(Low Risk)
Ganciclovir(Low Risk)
Ertapenem(Safe)
Econazole(Safe)
Gatifloxacin(Low Risk)
Malathion(Low Risk)
Cefoxitin(Safe)
Zidovudine(Low Risk)
Enoxacin(Low Risk)
Ofloxacin(Safe)
Lindane(Unsafe)
Cefotetan(Safe)
Tenofovir(Safe)
Doxycycline(Low Risk)
Famciclovir(Low Risk)
Amikacin(Safe)
Efavirenz(Unsafe)
Neomycin(Safe)
Erythromycin(Low Risk)
Didanosine(Unsafe)
Nafcillin(Safe)
Cefixime(Safe)
Demeclocycline(Low Risk)
Clindamycin(Low Risk)
Moxifloxacin(Low Risk)
Cefepime(Safe)
Saquinavir(Unsafe)
Primaquine(Low Risk)
Methicillin(Low Risk)
Cefdinir(Safe)
Ritonavir(Unsafe)
Naftifine(Safe)
Atovaquone(Low Risk)
Abacavir(Safe)
Meropenem(Safe)
Rifaximin(Safe)
Cefazolin(Safe)
Linezolid(Low Risk)
Acyclovir(Safe)
Nevirapine(Low Risk)
Lomefloxacin(Low Risk)
Cefaclor(Safe)
Nelfinavir(Unsafe)
Quinine(Safe)
Levofloxacin(Low Risk)
Kanamycin(Safe)
Amantadine(Low Risk)
Dapsone(Low Risk)
Valganciclovir(Low Risk)
Pyrantel(Safe)
Malathion(Low Risk)
Lindane(Unsafe)
Primaquine(Low Risk)
Atovaquone(Low Risk)
Quinine(Safe)
Malathion(Low Risk)
Lindane(Unsafe)

Synonyms of O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.