Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 7608? Is HSDB 7608 safe for nursing mother and child? Does HSDB 7608 extracts into breast milk? Does HSDB 7608 has any long term or short term side effects on infants? Can HSDB 7608 influence milk supply or can HSDB 7608 decrease milk supply in lactating mothers?

Answer by DrLact: About HSDB 7608 usage in lactation

Because HSDB 7608 is not orally absorbed, HSDB 7608 does not reach the breastmilk or adversely affect the breastfed infant after maternal administration. A suspension of HSDB 7608 has been added directly to breastmilk to lower the phosphorus concentration of milk. This could be a useful maneuver for breastmilk use in infants with renal impairment; however, clinical use has not been reported. In addition to lowering average phosphorus content by 65% to over 80%, the calcium content of breastmilk was reduced by almost as much and the casein content also decreased somewhat. With HSDB 7608 hydrochloride, the chloride content increased by 60% and the pH changed from 6.8 to 7.8, although pH appears to rebound over time.[1][2] Addition of large amounts of HSDB 7608 to artificial formula also lowers the copper, magnesium, manganese, potassium, sulfur and zinc concentrations by about 20%.[3] Similar reductions might occur with breastmilk.
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