Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-941N5DUU5C? Is UNII-941N5DUU5C safe for nursing mother and child? Does UNII-941N5DUU5C extracts into breast milk? Does UNII-941N5DUU5C has any long term or short term side effects on infants? Can UNII-941N5DUU5C influence milk supply or can UNII-941N5DUU5C decrease milk supply in lactating mothers?

Answer by DrLact: About UNII-941N5DUU5C usage in lactation

Because UNII-941N5DUU5C is not orally absorbed, UNII-941N5DUU5C does not reach the breastmilk or adversely affect the breastfed infant after maternal administration. A suspension of UNII-941N5DUU5C has been added directly to breastmilk to lower the phosphorus concentration of milk. This could be a useful maneuver for breastmilk use in infants with renal impairment; however, clinical use has not been reported. In addition to lowering average phosphorus content by 65% to over 80%, the calcium content of breastmilk was reduced by almost as much and the casein content also decreased somewhat. With UNII-941N5DUU5C hydrochloride, the chloride content increased by 60% and the pH changed from 6.8 to 7.8, although pH appears to rebound over time.[1][2] Addition of large amounts of UNII-941N5DUU5C to artificial formula also lowers the copper, magnesium, manganese, potassium, sulfur and zinc concentrations by about 20%.[3] Similar reductions might occur with breastmilk.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.