I am a breastfeeding mother and i want to know if it is safe to use UNII-55KHL3P693? Is UNII-55KHL3P693 safe for nursing mother and child? Does UNII-55KHL3P693 extracts into breast milk? Does UNII-55KHL3P693 has any long term or short term side effects on infants? Can UNII-55KHL3P693 influence milk supply or can UNII-55KHL3P693 decrease milk supply in lactating mothers?
No information is available on the clinical use of UNII-55KHL3P693 during breastfeeding. Because UNII-55KHL3P693 is a large protein molecule with a molecular weight of about 147,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, UNII-55KHL3P693 should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. UNII-55KHL3P693 is a human immunoglobulin G1 (IgG4) antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G in mature milk by 60 to 79%.[1][2] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Specific IgG subclasses decreased by different amounts, with IgG4 activity decreasing by about %.[3] None of the studies measured IgG activity.
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