Question

I am a breastfeeding mother and i want to know if it is safe to use Valine? Is Valine safe for nursing mother and child? Does Valine extracts into breast milk? Does Valine has any long term or short term side effects on infants? Can Valine influence milk supply or can Valine decrease milk supply in lactating mothers?

Valine lactation summary

Valine is safe in breastfeeding
  • DrLact safety Score for Valine is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Valine is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Valine does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Valine safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Valine usage in lactation

Leucine, isoleucine and valine are essential amino acids which are not produced by the body and must be ingested from the diet.They are found in large amount in muscles of meat and are necessary for synthesis of proteins in the body.They are wasted during liver disorders, high catabolic processes (cancer, burns) and also used for dietary supplementation in sport and fitness. At latest update no published data on excretion into breast milk were found.Around 20 amino acids (8 of them are essential) are normally present in breastmilk to which they reach through a selective-transport system of alveolar mammary epithelium (Ramirez 2001) with higher concentrations observed in the milk of obese mothers ( De Luca 2016).Its concentration is higher in the plasma of both mother and newborn after vaginal delivery than after cesarean section. (Schulpis 2009).BCAA supplementation does not alter the levels of prolactin (Bianchi 1992). These are natural components of the body that are devoid of toxicity even at higher doses than those recommended (AESAN 2012) without harmful effect while breastfeeding.
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