Is AEP 1 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use AEP 1? Is AEP 1 safe for nursing mother and child? Does AEP 1 extracts into breast milk? Does AEP 1 has any long term or short term side effects on infants? Can AEP 1 influence milk supply or can AEP 1 decrease milk supply in lactating mothers?

Because AEP 1 is not orally absorbed, it is unlikely to reach the breastmilk or adversely affect the breastfed infant after maternal administration. No special precautions are required. A suspension of AEP 1 has been added directly to breastmilk to lower the potassium concentration of milk for use in infants with renal impairment. In addition to lowering average potassium content by 65%, the calcium content of breastmilk was reduced by 84%.[1] Infants given either expressed breastmilk, formula or a combination of both had their average serum potassium levels decreased by 24% from 6.3 to 4.8 mEq/L. Serum calcium and creatinine also decreased slightly. The infants had no clinically noticeable side effects.[2] Addition of large amounts of AEP 1 to artificial formula also lowers the calcium, copper, manganese, phosphorus, sulfur and zinc concentrations; whereas the iron, sodium and sulfur content of formulas are increased.[3] Similar changes might occur with breastmilk.