Is Penbutolol Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Penbutolol? Is Penbutolol safe for nursing mother and child? Does Penbutolol extracts into breast milk? Does Penbutolol has any long term or short term side effects on infants? Can Penbutolol influence milk supply or can Penbutolol decrease milk supply in lactating mothers?

Based on its physicochemical properties, penbutolol appears to present a low-risk to the breastfed infant. Because there is no published experience with penbutolol during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

Relevant published information on penbutolol was not found as of the revision date. A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking penbutolol.[2]

Relevant published information on the effects of beta-blockade or penbutolol during normal lactation was not found as of the revision date. A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[3]