Question

I am a breastfeeding mother and i want to know if it is safe to use TAK-375? Is TAK-375 safe for nursing mother and child? Does TAK-375 extracts into breast milk? Does TAK-375 has any long term or short term side effects on infants? Can TAK-375 influence milk supply or can TAK-375 decrease milk supply in lactating mothers?

Answer by DrLact: About TAK-375 usage in lactation

No information is available on the use of TAK-375 during breastfeeding. If TAK-375 is required by the mother, it is not a reason to discontinue breastfeeding. Monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of psychotropic drugs.

TAK-375 Possible Effects in Breastfeeding

Prolactin levels increased by 4.9 mcg/L (34%) in non-breastfeeding women with chronic insomnia who were taking TAK-375 16 mg nightly for 6 months. No clinical symptoms of hyperprolactinemia were reported.[1] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

Alternate Drugs

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