Question

I am a breastfeeding mother and i want to know if it is safe to use CDP-870? Is CDP-870 safe for nursing mother and child? Does CDP-870 extracts into breast milk? Does CDP-870 has any long term or short term side effects on infants? Can CDP-870 influence milk supply or can CDP-870 decrease milk supply in lactating mothers?

CDP-870 lactation summary

CDP-870 is safe in breastfeeding
  • DrLact safety Score for CDP-870 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of CDP-870 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that CDP-870 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of CDP-870 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About CDP-870 usage in lactation

Monoclonal antibody directed against TNF (tumoral necrosis factor) that is used for treatment of autoimmune diseases like Rheumatoid Arthritis and Crohn's Disease. Probably because of a high molecular weight, no detectable traces have been found in mother's milk. It is not absorbed by the gut which is even more protective for the nursing infant. No harm effect has been shown among breastfed infants whose mothers were treated with this medication. Avoid using it in the two post-partum weeks since significant excretion into the milk within the first 3 - 4 days after delivery and absorption by the infant is possible.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.