Question

I am a breastfeeding mother and i want to know if it is safe to use PDL-063? Is PDL-063 safe for nursing mother and child? Does PDL-063 extracts into breast milk? Does PDL-063 has any long term or short term side effects on infants? Can PDL-063 influence milk supply or can PDL-063 decrease milk supply in lactating mothers?

Answer by DrLact: About PDL-063 usage in lactation

No information is available on the clinical use of PDL-063 during breastfeeding. Because PDL-063 is a large protein molecule with a molecular weight of 148,100, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. However, PDL-063 is administered with dexamethasone and lenalidomide, two drugs which also have no information on use in nursing mothers. The manufacturer recommends that women receiving PDL-063 should not breastfeed.

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