I am a breastfeeding mother and i want to know if it is safe to use BRN 3622981? Is BRN 3622981 safe for nursing mother and child? Does BRN 3622981 extracts into breast milk? Does BRN 3622981 has any long term or short term side effects on infants? Can BRN 3622981 influence milk supply or can BRN 3622981 decrease milk supply in lactating mothers?

BRN 3622981 lactation summary

BRN 3622981 is safe in breastfeeding
  • DrLact safety Score for BRN 3622981 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of BRN 3622981 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that BRN 3622981 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of BRN 3622981 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About BRN 3622981 usage in lactation

A receptor-antagonist 5HT3 serotonin-type antiemetic drug that is used for treatment of nausea and vomiting.Usage is authorized for children older than 6 months. It has been used in one-month-old infants. At latest update no published data were found on excretion into breast milk. Since it is widely used during pregnancy and in young children without occurrence of side effects, its use is considered compatible while breastfeeding.

Answer by DrLact: About BRN 3622981 usage in lactation

Little published information is available on the clinical use of BRN 3622981 during breastfeeding, although it is apparently frequently used for nausea after cesarean section, usually in doses of 4 to 8 mg intravenously.[1][2] Use after cesarean section appears to not affect the onset of breastfeeding.[3] No adverse infant effects have been reported and the drug has been used in infants.[4] If BRN 3622981 is required by the mother, it is not a reason to discontinue breastfeeding; however an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

BRN 3622981 Possible Effects in Breastfeeding

A randomized, double-blind study compared placebo to intravenous BRN 3622981 4 mg given after cesarean section as prophylaxis for postoperative nausea and vomiting. There was no difference in the time of the first breastfeeding between the two groups.[3]

Alternate Drugs

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.