Is UNII-E0QN3D755O Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-E0QN3D755O? Is UNII-E0QN3D755O safe for nursing mother and child? Does UNII-E0QN3D755O extracts into breast milk? Does UNII-E0QN3D755O has any long term or short term side effects on infants? Can UNII-E0QN3D755O influence milk supply or can UNII-E0QN3D755O decrease milk supply in lactating mothers?
UNII-E0QN3D755O lactation summary
- DrLact safety Score for UNII-E0QN3D755O is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of UNII-E0QN3D755O may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-E0QN3D755O may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using UNII-E0QN3D755O .
- Usage of UNII-E0QN3D755O is in contradiction to breastfeeding hence if it is must to use UNII-E0QN3D755O and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-E0QN3D755O usage in lactation
Anti-Parkinson drug, dopamine-agonist and synthetic ergotamine derivative that may inhibit prolactin release.
Answer by DrLact: About UNII-E0QN3D755O usage in lactation
UNII-E0QN3D755O is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries. It lowers serum prolactin and is approved in some countries for lactation suppression. Some experts recommend UNII-E0QN3D755O as a safer alternative to bromocriptine for lactation suppression, but others recommend avoiding all lactation suppressants.[1][2] Data are insufficient recommend one treatment for lactation suppression over another.[3]
UNII-E0QN3D755O Possible Effects in Breastfeeding
UNII-E0QN3D755O suppresses serum prolactin increases in a dose-related fashion.[4][5] Comparative studies have found UNII-E0QN3D755O comparable in efficacy to bromocriptine, although rebound lactation occurred in more patients treated with UNII-E0QN3D755O 0.4 mg daily than in those treated with bromocriptine 5 mg daily.[6][7] Rebound lactation appears to be less with a higher dose of 0.6 mg daily and with 15 days of therapy rather than 10 days.[8][9]
Alternate Drugs
Pramipexole(Unsafe)
Ropinirole(Unsafe)
Levodopa(Unsafe)
Cabergoline(Unsafe)
Bromocriptine(Unsafe)
Amantadine(Low Risk)
Lisuride(Dangerous)
Pramipexole(Unsafe)
Ropinirole(Unsafe)
Cabergoline(Unsafe)
Bromocriptine(Unsafe)
Lisuride(Dangerous)
Lisuride(Dangerous)