Is ICL 670A Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use ICL 670A? Is ICL 670A safe for nursing mother and child? Does ICL 670A extracts into breast milk? Does ICL 670A has any long term or short term side effects on infants? Can ICL 670A influence milk supply or can ICL 670A decrease milk supply in lactating mothers?

ICL 670A appears to pass into milk very poorly. Although Australian guidelines recommend against breastfeeding during ICL 670A treatment,[1] these were published before a case report of an infant being safely breastfed by a mother with beta-thalassemia receiving ICL 670A and finding of no drug in breastmilk.[2] If ICL 670A is required by the mother, it is not a reason to discontinue breastfeeding. However, since little published information is available on the use of ICL 670A during breastfeeding, monitoring of the infant's serum iron is recommended.

A woman with beta-thalassemia was started on ICL 670A 2250 mg (35 mg/kg) daily immediately postpartum and exclusively breastfed her infant. Blood samples were taken from the infant at 1, 10 and 30 days postpartum. Serum ferritin levels were 190, 218, and 96 mcg/L, respectively (normal range 22-275 mcg/L). Serum iron levels were 101, 77 and 71 mcg/dL, respectively (normal range 60-170 mcg/dL). The infant's growth was normal during the first month at the 41st percentile.[2]