Question

I am a breastfeeding mother and i want to know if it is safe to use Ro 24-7375? Is Ro 24-7375 safe for nursing mother and child? Does Ro 24-7375 extracts into breast milk? Does Ro 24-7375 has any long term or short term side effects on infants? Can Ro 24-7375 influence milk supply or can Ro 24-7375 decrease milk supply in lactating mothers?

Ro 24-7375 lactation summary

Ro 24-7375 usage has low risk in breastfeeding
  • DrLact safety Score for Ro 24-7375 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Ro 24-7375 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Ro 24-7375 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Ro 24-7375 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Ro 24-7375 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Ro 24-7375 usage in lactation

Used for prevention of kidney transplant rejection.

Answer by DrLact: About Ro 24-7375 usage in lactation

No information is available on the clinical use of Ro 24-7375 during breastfeeding. Because Ro 24-7375 is a large protein molecule with a molecular weight of about 144,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, Ro 24-7375 should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Some authors recommend avoiding breastfeeding with Ro 24-7375.[1][2]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.