Question

I am a breastfeeding mother and i want to know if it is safe to use DAC HYP? Is DAC HYP safe for nursing mother and child? Does DAC HYP extracts into breast milk? Does DAC HYP has any long term or short term side effects on infants? Can DAC HYP influence milk supply or can DAC HYP decrease milk supply in lactating mothers?

DAC HYP lactation summary

DAC HYP usage has low risk in breastfeeding
  • DrLact safety Score for DAC HYP is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of DAC HYP may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that DAC HYP may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of DAC HYP low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using DAC HYP We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About DAC HYP usage in lactation

Used for prevention of kidney transplant rejection.

Answer by DrLact: About DAC HYP usage in lactation

No information is available on the clinical use of DAC HYP during breastfeeding. Because DAC HYP is a large protein molecule with a molecular weight of about 144,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, DAC HYP should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Some authors recommend avoiding breastfeeding with DAC HYP.[1][2]

Alternate Drugs

Reslizumab
Elotuzumab
Daratumumab
Mepolizumab
Dinutuximab
Pembrolizumab
Vedolizumab
Tocilizumab(Low Risk)
Alemtuzumab(Low Risk)
Golimumab
Adalimumab(Safe)
Tildrakizumab
Benralizumab
Inotuzumab Ozogamicin
Daclizumab(Low Risk)
Ixekizumab

Synonyms of DAC HYP

Zenapax
Ro 24-7375
UNII-CUJ2MVI71Y
DAC-HYP
Anti-TAC
Zinbryta
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.