Question

I am a breastfeeding mother and i want to know if it is safe to use Anti-TAC? Is Anti-TAC safe for nursing mother and child? Does Anti-TAC extracts into breast milk? Does Anti-TAC has any long term or short term side effects on infants? Can Anti-TAC influence milk supply or can Anti-TAC decrease milk supply in lactating mothers?

Anti-TAC lactation summary

Anti-TAC usage has low risk in breastfeeding
  • DrLact safety Score for Anti-TAC is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Anti-TAC may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Anti-TAC may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Anti-TAC low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Anti-TAC We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Anti-TAC usage in lactation

Used for prevention of kidney transplant rejection.

Answer by DrLact: About Anti-TAC usage in lactation

No information is available on the clinical use of Anti-TAC during breastfeeding. Because Anti-TAC is a large protein molecule with a molecular weight of about 144,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, Anti-TAC should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Some authors recommend avoiding breastfeeding with Anti-TAC.[1][2]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.