Question

I am a breastfeeding mother and i want to know if it is safe to use 2-CDA? Is 2-CDA safe for nursing mother and child? Does 2-CDA extracts into breast milk? Does 2-CDA has any long term or short term side effects on infants? Can 2-CDA influence milk supply or can 2-CDA decrease milk supply in lactating mothers?

2-CDA lactation summary

2-CDA is dangerous in breastfeeding
  • DrLact safety Score for 2-CDA is 7 out of 8 which is considered Dangerous as per our analyses.
  • A safety Score of 7 indicates that usage of 2-CDA may cause toxic or severe side effects in breastfed baby.
  • Our study of different scientific research indicates that 2-CDA may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using 2-CDA .
  • Usage of 2-CDA is in contradiction to breastfeeding hence if it is must to use 2-CDA and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 2-CDA usage in lactation

Drug is cleared from the body in 7 elimination half-lives. Resuming breastfeeding is likely safe after 48 hours of pumping-and-dumping.

Answer by DrLact: About 2-CDA usage in lactation

Because there is no published experience with 2-CDA during breastfeeding, it should be avoided during breastfeeding, especially while nursing a newborn or preterm infant.[1][2] One group of authors recommends withholding breastfeeding for at 48 hours after a dose and longer in patients with impaired kidney function.[2] Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[3] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[4]

Alternate Drugs

Cetuximab(Unsafe)
Pazopanib(Unsafe)
Cisplatin(Unsafe)
Docetaxel(Dangerous)
Carboplatin(Dangerous)
Busulfan(Dangerous)
Vinblastine(Dangerous)
Paclitaxel(Dangerous)
Bleomycin(Dangerous)
Vinorelbine(Dangerous)
Erlotinib(Unsafe)
Dacarbazine(Dangerous)
Vincristine(Dangerous)
Fluorouracil(Dangerous)
Tamoxifen(Dangerous)
Cladribine(Dangerous)
Letrozole(Dangerous)
Exemestane(Dangerous)
Alemtuzumab(Low Risk)
Dactinomycin(Dangerous)
Thioguanine(Dangerous)
Mitoxantrone(Dangerous)
Dasatinib(Unsafe)
Rituximab(Low Risk)
Nilotinib(Unsafe)
Bevacizumab(Low Risk)
Hydroxyurea(Low Risk)
Etoposide(Dangerous)
Gemcitabine(Dangerous)
Doxorubicin(Dangerous)
Trastuzumab(Unsafe)
Nivolumab(Unsafe)
Imatinib(Unsafe)
Ipilimumab(Unsafe)
Cyclophosphamide(Dangerous)
Pimecrolimus(Low Risk)
Methotrexate(Low Risk)
Fluorouracil(Dangerous)
Cladribine(Dangerous)
Alemtuzumab(Low Risk)
Fingolimod(Unsafe)
Sirolimus(Unsafe)
Gemcitabine(Dangerous)
Everolimus(Unsafe)
Leflunomide(Dangerous)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.