Question

I am a breastfeeding mother and i want to know if it is safe to use Leustatin? Is Leustatin safe for nursing mother and child? Does Leustatin extracts into breast milk? Does Leustatin has any long term or short term side effects on infants? Can Leustatin influence milk supply or can Leustatin decrease milk supply in lactating mothers?

Leustatin lactation summary

Leustatin is dangerous in breastfeeding
  • DrLact safety Score for Leustatin is 7 out of 8 which is considered Dangerous as per our analyses.
  • A safety Score of 7 indicates that usage of Leustatin may cause toxic or severe side effects in breastfed baby.
  • Our study of different scientific research indicates that Leustatin may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Leustatin .
  • Usage of Leustatin is in contradiction to breastfeeding hence if it is must to use Leustatin and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Leustatin usage in lactation

Drug is cleared from the body in 7 elimination half-lives. Resuming breastfeeding is likely safe after 48 hours of pumping-and-dumping.

Answer by DrLact: About Leustatin usage in lactation

Because there is no published experience with Leustatin during breastfeeding, it should be avoided during breastfeeding, especially while nursing a newborn or preterm infant.[1][2] One group of authors recommends withholding breastfeeding for at 48 hours after a dose and longer in patients with impaired kidney function.[2] Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[3] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[4]

Alternate Drugs

Etoposide(Dangerous)
Trastuzumab(Unsafe)
Gemcitabine(Dangerous)
Doxorubicin(Dangerous)
Imatinib(Unsafe)
Nivolumab(Unsafe)
Ipilimumab(Unsafe)
Cyclophosphamide(Dangerous)
Cetuximab(Unsafe)
Pazopanib(Unsafe)
Cisplatin(Unsafe)
Docetaxel(Dangerous)
Carboplatin(Dangerous)
Busulfan(Dangerous)
Vinblastine(Dangerous)
Paclitaxel(Dangerous)
Bleomycin(Dangerous)
Vinorelbine(Dangerous)
Fluorouracil(Dangerous)
Erlotinib(Unsafe)
Dacarbazine(Dangerous)
Vincristine(Dangerous)
Letrozole(Dangerous)
Tamoxifen(Dangerous)
Cladribine(Dangerous)
Exemestane(Dangerous)
Alemtuzumab(Low Risk)
Rituximab(Low Risk)
Dactinomycin(Dangerous)
Thioguanine(Dangerous)
Mitoxantrone(Dangerous)
Dasatinib(Unsafe)
Nilotinib(Unsafe)
Bevacizumab(Low Risk)
Hydroxyurea(Low Risk)
Gemcitabine(Dangerous)
Everolimus(Unsafe)
Leflunomide(Dangerous)
Pimecrolimus(Low Risk)
Fluorouracil(Dangerous)
Methotrexate(Low Risk)
Cladribine(Dangerous)
Alemtuzumab(Low Risk)
Fingolimod(Unsafe)
Sirolimus(Unsafe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.