Is NSC 105014-F Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use NSC 105014-F? Is NSC 105014-F safe for nursing mother and child? Does NSC 105014-F extracts into breast milk? Does NSC 105014-F has any long term or short term side effects on infants? Can NSC 105014-F influence milk supply or can NSC 105014-F decrease milk supply in lactating mothers?
NSC 105014-F lactation summary
- DrLact safety Score for NSC 105014-F is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of NSC 105014-F may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that NSC 105014-F may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using NSC 105014-F .
- Usage of NSC 105014-F is in contradiction to breastfeeding hence if it is must to use NSC 105014-F and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About NSC 105014-F usage in lactation
Drug is cleared from the body in 7 elimination half-lives. Resuming breastfeeding is likely safe after 48 hours of pumping-and-dumping.
Answer by DrLact: About NSC 105014-F usage in lactation
Because there is no published experience with NSC 105014-F during breastfeeding, it should be avoided during breastfeeding, especially while nursing a newborn or preterm infant.[1][2] One group of authors recommends withholding breastfeeding for at 48 hours after a dose and longer in patients with impaired kidney function.[2] Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[3] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[4]
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