Is 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine? Is 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine safe for nursing mother and child? Does 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine extracts into breast milk? Does 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine has any long term or short term side effects on infants? Can 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine influence milk supply or can 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine decrease milk supply in lactating mothers?
2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine lactation summary
- DrLact safety Score for 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine .
- Usage of 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine is in contradiction to breastfeeding hence if it is must to use 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine usage in lactation
Drug is cleared from the body in 7 elimination half-lives. Resuming breastfeeding is likely safe after 48 hours of pumping-and-dumping.
Answer by DrLact: About 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine usage in lactation
Because there is no published experience with 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine during breastfeeding, it should be avoided during breastfeeding, especially while nursing a newborn or preterm infant.[1][2] One group of authors recommends withholding breastfeeding for at 48 hours after a dose and longer in patients with impaired kidney function.[2] Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[3] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[4]
Alternate Drugs
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Mercaptopurine(Safe)
Hydroxyurea(Low Risk)
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