Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 7564? Is HSDB 7564 safe for nursing mother and child? Does HSDB 7564 extracts into breast milk? Does HSDB 7564 has any long term or short term side effects on infants? Can HSDB 7564 influence milk supply or can HSDB 7564 decrease milk supply in lactating mothers?

HSDB 7564 lactation summary

HSDB 7564 is dangerous in breastfeeding
  • DrLact safety Score for HSDB 7564 is 7 out of 8 which is considered Dangerous as per our analyses.
  • A safety Score of 7 indicates that usage of HSDB 7564 may cause toxic or severe side effects in breastfed baby.
  • Our study of different scientific research indicates that HSDB 7564 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using HSDB 7564 .
  • Usage of HSDB 7564 is in contradiction to breastfeeding hence if it is must to use HSDB 7564 and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 7564 usage in lactation

Drug is cleared from the body in 7 elimination half-lives. Resuming breastfeeding is likely safe after 48 hours of pumping-and-dumping.

Answer by DrLact: About HSDB 7564 usage in lactation

Because there is no published experience with HSDB 7564 during breastfeeding, it should be avoided during breastfeeding, especially while nursing a newborn or preterm infant.[1][2] One group of authors recommends withholding breastfeeding for at 48 hours after a dose and longer in patients with impaired kidney function.[2] Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[3] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[4]

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Docetaxel(Dangerous)
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Fluorouracil(Dangerous)
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Tamoxifen(Dangerous)
Cladribine(Dangerous)
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Exemestane(Dangerous)
Alemtuzumab(Low Risk)
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Thioguanine(Dangerous)
Mitoxantrone(Dangerous)
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Cladribine(Dangerous)
Alemtuzumab(Low Risk)
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Sirolimus(Unsafe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.