Is CCRIS 9374 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use CCRIS 9374? Is CCRIS 9374 safe for nursing mother and child? Does CCRIS 9374 extracts into breast milk? Does CCRIS 9374 has any long term or short term side effects on infants? Can CCRIS 9374 influence milk supply or can CCRIS 9374 decrease milk supply in lactating mothers?
CCRIS 9374 lactation summary
- DrLact safety Score for CCRIS 9374 is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of CCRIS 9374 may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that CCRIS 9374 may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using CCRIS 9374 .
- Usage of CCRIS 9374 is in contradiction to breastfeeding hence if it is must to use CCRIS 9374 and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About CCRIS 9374 usage in lactation
Drug is cleared from the body in 7 elimination half-lives. Resuming breastfeeding is likely safe after 48 hours of pumping-and-dumping.
Answer by DrLact: About CCRIS 9374 usage in lactation
Because there is no published experience with CCRIS 9374 during breastfeeding, it should be avoided during breastfeeding, especially while nursing a newborn or preterm infant.[1][2] One group of authors recommends withholding breastfeeding for at 48 hours after a dose and longer in patients with impaired kidney function.[2] Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[3] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[4]
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