I am a breastfeeding mother and i want to know if it is safe to use 68Ga-DOTA-Tyr3-octreotide? Is 68Ga-DOTA-Tyr3-octreotide safe for nursing mother and child? Does 68Ga-DOTA-Tyr3-octreotide extracts into breast milk? Does 68Ga-DOTA-Tyr3-octreotide has any long term or short term side effects on infants? Can 68Ga-DOTA-Tyr3-octreotide influence milk supply or can 68Ga-DOTA-Tyr3-octreotide decrease milk supply in lactating mothers?
68Ga-DOTA-Tyr3-octreotide is used for localization of somatostatin receptor positive neuroendocrine tumors. It can found in lactating breasts in higher than usual amounts.[1] Labeling in the U.S. advises nursing mothers to pump and discard breastmilk for 12 hours after a dose, based on isotope's physical half-life alone. However, a group of investigators who measured breastmilk excretion in one woman recommend pumping and discarding breastmilk for 4 hours after the dose, then resuming breastfeeding.[2] Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital. When the radioactivity is at a safe level she may resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.[3] Nursing mothers should not work with radioactive substances used in PET scans in their workplace.[4]
Disclaimer:
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.