Is Ampicillin Trihydrate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Ampicillin Trihydrate? Is Ampicillin Trihydrate safe for nursing mother and child? Does Ampicillin Trihydrate extracts into breast milk? Does Ampicillin Trihydrate has any long term or short term side effects on infants? Can Ampicillin Trihydrate influence milk supply or can Ampicillin Trihydrate decrease milk supply in lactating mothers?
Ampicillin Trihydrate lactation summary
- DrLact safety Score for Ampicillin Trihydrate is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Ampicillin Trihydrate is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Ampicillin Trihydrate does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Ampicillin Trihydrate safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Ampicillin Trihydrate usage in lactation
Ampicillin is excreted in breast milk in clinically insignificant amounts (Rowe, 2013, Mylonas, 2011, Zhang, 1997, Fulton, 1992, Campbell 1991, Matsuda 1984), much lower than the dose used for newborns and infants ( Chin, 2000; Reali, 2005). No side effects have been observed in infants whose mothers were taking it except for some episodes of diarrhea or candidiasis due to altered intestinal flora (Chin, 2000). The possible negativity of cultures in febrile infants whose mothers take antibiotics should be taken into account, as well as the possibility of gastroenteritis due to altered intestinal flora (Benyamini 2005, Ito 1993, Kafetzis 1981).