Is AVE0005 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use AVE0005? Is AVE0005 safe for nursing mother and child? Does AVE0005 extracts into breast milk? Does AVE0005 has any long term or short term side effects on infants? Can AVE0005 influence milk supply or can AVE0005 decrease milk supply in lactating mothers?

This record refers to the use of intravitreal AVE0005 for macular degeneration. No information is available on the use of AVE0005 during breastfeeding. The manufacturer estimates that after intravitreal administration of 2 mg, the mean maximum plasma concentration of free AVE0005 is more than 100-fold lower than the concentration of AVE0005 required to half-maximally bind systemic vascular endothelial growth factor. Additionally, AVE0005 is a large protein molecule with a molecular weight of 115,000, Therefore, the amount in breastmilk is likely to be clinically unimportant after intravitreal injection. However, the manufacturer recommends avoiding the drug during breastfeeding.