Is VEGF Trap - regeneron Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use VEGF Trap - regeneron? Is VEGF Trap - regeneron safe for nursing mother and child? Does VEGF Trap - regeneron extracts into breast milk? Does VEGF Trap - regeneron has any long term or short term side effects on infants? Can VEGF Trap - regeneron influence milk supply or can VEGF Trap - regeneron decrease milk supply in lactating mothers?

This record refers to the use of intravitreal VEGF Trap - regeneron for macular degeneration. No information is available on the use of VEGF Trap - regeneron during breastfeeding. The manufacturer estimates that after intravitreal administration of 2 mg, the mean maximum plasma concentration of free VEGF Trap - regeneron is more than 100-fold lower than the concentration of VEGF Trap - regeneron required to half-maximally bind systemic vascular endothelial growth factor. Additionally, VEGF Trap - regeneron is a large protein molecule with a molecular weight of 115,000, Therefore, the amount in breastmilk is likely to be clinically unimportant after intravitreal injection. However, the manufacturer recommends avoiding the drug during breastfeeding.