Is Bay 86-5321 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Bay 86-5321? Is Bay 86-5321 safe for nursing mother and child? Does Bay 86-5321 extracts into breast milk? Does Bay 86-5321 has any long term or short term side effects on infants? Can Bay 86-5321 influence milk supply or can Bay 86-5321 decrease milk supply in lactating mothers?

This record refers to the use of intravitreal Bay 86-5321 for macular degeneration. No information is available on the use of Bay 86-5321 during breastfeeding. The manufacturer estimates that after intravitreal administration of 2 mg, the mean maximum plasma concentration of free Bay 86-5321 is more than 100-fold lower than the concentration of Bay 86-5321 required to half-maximally bind systemic vascular endothelial growth factor. Additionally, Bay 86-5321 is a large protein molecule with a molecular weight of 115,000, Therefore, the amount in breastmilk is likely to be clinically unimportant after intravitreal injection. However, the manufacturer recommends avoiding the drug during breastfeeding.