Question

I am a breastfeeding mother and i want to know if it is safe to use Eylea? Is Eylea safe for nursing mother and child? Does Eylea extracts into breast milk? Does Eylea has any long term or short term side effects on infants? Can Eylea influence milk supply or can Eylea decrease milk supply in lactating mothers?

Answer by DrLact: About Eylea usage in lactation

This record refers to the use of intravitreal Eylea for macular degeneration. No information is available on the use of Eylea during breastfeeding. The manufacturer estimates that after intravitreal administration of 2 mg, the mean maximum plasma concentration of free Eylea is more than 100-fold lower than the concentration of Eylea required to half-maximally bind systemic vascular endothelial growth factor. Additionally, Eylea is a large protein molecule with a molecular weight of 115,000, Therefore, the amount in breastmilk is likely to be clinically unimportant after intravitreal injection. However, the manufacturer recommends avoiding the drug during breastfeeding.
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