Question

I am a breastfeeding mother and i want to know if it is safe to use Zaltrap? Is Zaltrap safe for nursing mother and child? Does Zaltrap extracts into breast milk? Does Zaltrap has any long term or short term side effects on infants? Can Zaltrap influence milk supply or can Zaltrap decrease milk supply in lactating mothers?

Answer by DrLact: About Zaltrap usage in lactation

This record refers to the use of intravitreal Zaltrap for macular degeneration. No information is available on the use of Zaltrap during breastfeeding. The manufacturer estimates that after intravitreal administration of 2 mg, the mean maximum plasma concentration of free Zaltrap is more than 100-fold lower than the concentration of Zaltrap required to half-maximally bind systemic vascular endothelial growth factor. Additionally, Zaltrap is a large protein molecule with a molecular weight of 115,000, Therefore, the amount in breastmilk is likely to be clinically unimportant after intravitreal injection. However, the manufacturer recommends avoiding the drug during breastfeeding.
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