Is Recombinant Factor VIII Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Recombinant Factor VIII? Is Recombinant Factor VIII safe for nursing mother and child? Does Recombinant Factor VIII extracts into breast milk? Does Recombinant Factor VIII has any long term or short term side effects on infants? Can Recombinant Factor VIII influence milk supply or can Recombinant Factor VIII decrease milk supply in lactating mothers?
Recombinant Factor VIII lactation summary
- DrLact safety Score for Recombinant Factor VIII is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Recombinant Factor VIII is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Recombinant Factor VIII does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Recombinant Factor VIII safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Recombinant Factor VIII usage in lactation
We are working on a comment for this product.
Answer by DrLact: About Recombinant Factor VIII usage in lactation
No information is available on the clinical use of Recombinant Factor VIII (coagulation factor VIII) during breastfeeding. Because it is a large protein molecule, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, Recombinant Factor VIII should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.